Understanding the Different Types of PGT: PGT-A, PGT-SR, PGT-M, and Ni-PGT

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We explore the different types of Preimplantation Genetic Testing (PGT) available to patients undergoing fertility treatment. In this article, we will delve into the uses and benefits of PGT-A, PGT-SR, PGT-M, and Ni-PGT. By understanding these types of PGT, you can make informed decisions in collaboration with your fertility specialist and increase the chances of a successful pregnancy.

 

PGT-A (Aneuploidy Testing)

Uses: PGT-A is prescribed for individuals or couples with advanced maternal age, recurrent miscarriages, or multiple failed IVF cycles.

Purpose: It helps identify embryos with the correct number of chromosomes, reducing the risk of implantation failure and miscarriage.

 

PGT-SR (Structural Rearrangements)

Uses: PGT-SR is recommended for individuals or couples with known structural rearrangements in their chromosomes.

Purpose: It assists in selecting embryos without the specific structural rearrangements, reducing the risk of passing them on to offspring.

 

PGT-M (Monogenic Disorders)

Uses: PGT-M is prescribed for individuals or couples with known monogenic disorders or a high risk of carrying such disorders.

Purpose: It allows for the identification of embryos free from specific monogenic disorders, increasing the chances of a healthy pregnancy.

 

Ni-PGT (Non-Invasive PGT)

Uses: Ni-PGT is used in cases where invasive embryo biopsy may not be possible or preferred.

Purpose: It enables genetic testing using non-invasive methods such as analyzing cell-free DNA from the embryo culture media, providing valuable genetic information without the need for embryo biopsy.

 

Benefits of PGT in Fertility Treatment

  • Increased pregnancy success rates by selecting genetically healthy embryos.
  • Reduced risk of miscarriage and implantation failure.
  • Decreased chances of passing on genetic disorders to offspring.
  • Enhanced family planning options and peace of mind.


Preimplantation Genetic Testing (PGT) offers different types, each with specific uses and benefits. Whether it’s PGT-A, PGT-SR, PGT-M, or Ni-PGT, these tests assist in selecting embryos with the desired genetic characteristics, increasing the chances of a successful pregnancy and fulfilling your family planning goals. Consult with our experienced fertility specialists at Aspire Fertility Centre to explore the different types of PGT and determine the most suitable option for your unique circumstances.


At Aspire Fertility Center in HSR Layout & Sarjapura, Bangalore, we recognize the challenges you may face and are here to provide not only the best medical care but also emotional support throughout the process. Our goal is to help you navigate this journey with strength, hope, and the assurance that you are not alone.